KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADRA1B
All Species:
22.12
Human Site:
S278
Identified Species:
48.67
UniProt:
P35368
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35368
NP_000670.1
520
56836
S278
K
G
H
N
P
R
S
S
I
A
V
K
L
F
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Q28524
418
44639
M220
F
Y
L
P
L
L
V
M
L
F
V
Y
A
R
V
Dog
Lupus familis
XP_536449
618
67286
S278
K
G
H
N
P
R
S
S
I
A
V
K
L
F
K
Cat
Felis silvestris
Mouse
Mus musculus
P97717
514
56400
S277
K
G
H
N
P
R
S
S
I
A
V
K
L
F
K
Rat
Rattus norvegicus
P15823
515
56567
S278
K
G
H
N
P
R
S
S
I
A
V
K
L
F
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506393
511
56733
S280
K
G
H
H
P
R
N
S
I
S
V
K
L
F
K
Chicken
Gallus gallus
XP_414483
507
56995
S282
K
G
H
N
S
R
N
S
L
A
L
K
L
L
K
Frog
Xenopus laevis
O42574
385
43291
C187
G
D
P
L
A
M
K
C
Y
E
D
P
G
C
C
Zebra Danio
Brachydanio rerio
XP_001922013
544
60273
K275
L
R
S
S
L
T
V
K
L
L
K
F
S
R
E
Tiger Blowfish
Takifugu rubipres
O42385
423
46982
G225
I
L
M
L
V
L
Y
G
R
I
F
K
A
A
R
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203873
574
63580
R274
P
G
H
Q
L
V
K
R
Q
N
S
A
N
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
32.1
76.8
N.A.
94.8
94.6
N.A.
77.6
70.9
28
54
25.9
N.A.
N.A.
N.A.
36.2
Protein Similarity:
100
N.A.
46.7
79.1
N.A.
96.3
96.5
N.A.
82.8
78.8
43.4
64.3
42.6
N.A.
N.A.
N.A.
49.6
P-Site Identity:
100
N.A.
6.6
100
N.A.
100
100
N.A.
80
66.6
0
0
6.6
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
N.A.
13.3
100
N.A.
100
100
N.A.
100
86.6
0
20
13.3
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
0
46
0
10
19
10
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
10
% C
% Asp:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% E
% Phe:
10
0
0
0
0
0
0
0
0
10
10
10
0
46
0
% F
% Gly:
10
64
0
0
0
0
0
10
0
0
0
0
10
0
0
% G
% His:
0
0
64
10
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
46
10
0
0
0
0
0
% I
% Lys:
55
0
0
0
0
0
19
10
0
0
10
64
0
0
55
% K
% Leu:
10
10
10
19
28
19
0
0
28
10
10
0
55
10
10
% L
% Met:
0
0
10
0
0
10
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
46
0
0
19
0
0
10
0
0
10
0
0
% N
% Pro:
10
0
10
10
46
0
0
0
0
0
0
10
0
0
0
% P
% Gln:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
0
10
0
0
0
55
0
10
10
0
0
0
0
19
10
% R
% Ser:
0
0
10
10
10
0
37
55
0
10
10
0
10
10
0
% S
% Thr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
10
10
19
0
0
0
55
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
10
0
10
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _